MedlinePlus Nicotine poisoning While vaping, it is easy to over dose on nicotine. With a traditional or analog cigarette, there is a beginning and end; when you first light the cigarette and when you have finished smoking the cigarette down to the butt or filter. Vaping does not necessarily have a beginning and end, except for maybe the beginning of your day when you wake up and the end of your day when you go to bed. You can vape all day, as much as you want (or can based on allowable schedule) and even grab a bottle a just have a cloud contest with friends. In doing this, it is possible to inhale more nicotine than you would have if you were still smoking cigarettes all day. Please be careful with eJuice containing nicotine, mixing your own eJuice containing nicotine and ALWAYS KEEP NICOTINE AWAY FROM CHILDREN. Vaping safely and if you are just starting out, it is better to start with a lower level of nicotine and have to move up, than to start to high and end up in the hospital. What are the Symptoms of Nicotine Overdose?